Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1

The herpes simplex virus 1 (HSV-1) genome is extremely rich in guanine tracts that fold into G-quadruplexes (G4s), nucleic acid secondary structures implicated in key biological functions. Viral G4s were visualized in HSV-1 infected cells, with massive virus cycle-dependent G4-formation peaking duri...

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Detalles Bibliográficos
Autores principales: Artusi, Sara, Ruggiero, Emanuela, Nadai, Matteo, Tosoni, Beatrice, Perrone, Rosalba, Ferino, Annalisa, Zanin, Irene, Xodo, Luigi, Flamand, Louis, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911665/
https://www.ncbi.nlm.nih.gov/pubmed/33525505
http://dx.doi.org/10.3390/v13020196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911665/
https://www.ncbi.nlm.nih.gov/pubmed/33525505
http://dx.doi.org/10.3390/v13020196

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