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NADPH Oxidase 5 Induces Changes in the Unfolded Protein Response in Human Aortic Endothelial Cells and in Endothelial-Specific Knock-in Mice

Oxidative stress constitutes a key molecular mechanism in the development of cardiovascular diseases. A potential relationship between reactive oxygen species (ROS) driven by the NADPH oxidase family (NOX) and the unfolded protein response (UPR) has been postulated. Nevertheless, there is a lack of...

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Detalles Bibliográficos
Autores principales: Cortés, Adriana, Pejenaute, Álvaro, Marqués, Javier, Izal, Íñigo, Cenoz, Silvia, Ansorena, Eduardo, Martínez-Irujo, Juan José, de Miguel, Carlos, Zalba, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911693/
https://www.ncbi.nlm.nih.gov/pubmed/33572841
http://dx.doi.org/10.3390/antiox10020194