Cargando…

NADPH Oxidase 5 Induces Changes in the Unfolded Protein Response in Human Aortic Endothelial Cells and in Endothelial-Specific Knock-in Mice

Oxidative stress constitutes a key molecular mechanism in the development of cardiovascular diseases. A potential relationship between reactive oxygen species (ROS) driven by the NADPH oxidase family (NOX) and the unfolded protein response (UPR) has been postulated. Nevertheless, there is a lack of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cortés, Adriana, Pejenaute, Álvaro, Marqués, Javier, Izal, Íñigo, Cenoz, Silvia, Ansorena, Eduardo, Martínez-Irujo, Juan José, de Miguel, Carlos, Zalba, Guillermo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911693/ https://www.ncbi.nlm.nih.gov/pubmed/33572841 http://dx.doi.org/10.3390/antiox10020194

Ejemplares similares

Induction of Cyclooxygenase-2 by Overexpression of the Human NADPH Oxidase 5 (NOX5) Gene in Aortic Endothelial Cells
por: Marqués, Javier, et al.
Publicado: (2020)

Structure, regulation, and physiological functions of NADPH oxidase 5 (NOX5)
por: García, Jorge G., et al.
Publicado: (2023)

NADPH Oxidase Overactivity Underlies Telomere Shortening in Human Atherosclerosis
por: Pejenaute, Álvaro, et al.
Publicado: (2020)

Endothelial NOX5 overexpression induces changes in the cardiac gene profile: potential impact in myocardial infarction?
por: Cortés, Adriana, et al.
Publicado: (2023)

NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)
por: Marqués, Javier, et al.
Publicado: (2022)

Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice
por: Cortés, Adriana, et al.
Publicado: (2021)

Endothelial Progenitor Cells and NADPH Oxidase Enzyme Activity in the Development of an Aortic Aneurysm
por: Bingol, Bilge, et al.
Publicado: (2022)

NADPH Oxidases in Aortic Aneurysms
por: Salmon, Morgan
Publicado: (2022)

Role of NADPH Oxidase-4 in Human Endothelial Progenitor Cells
por: Hakami, Nora Y., et al.
Publicado: (2017)

Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis
por: Ho, Florence, et al.
Publicado: (2022)

Endothelial NOX5 Expression Modulates Thermogenesis and Lipolysis in Mice Fed with a High-Fat Diet and 3T3-L1 Adipocytes through an Interleukin-6 Dependent Mechanism
por: García, Jorge G., et al.
Publicado: (2021)

Endothelial Nox5 Expression Modulates Glucose Uptake and Lipid Accumulation in Mice Fed a High-Fat Diet and 3T3-L1 Adipocytes Treated with Glucose and Palmitic Acid
por: García, Jorge G., et al.
Publicado: (2021)

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells
por: Lener, Barbara, et al.
Publicado: (2009)

Endothelial AIP1 Regulates Vascular Remodeling by Suppressing NADPH Oxidase-2
por: Zhang, Jiqin, et al.
Publicado: (2018)

Knock out of the NADPH oxidase Nox4 has no impact on life span in mice
por: Rezende, Flavia, et al.
Publicado: (2016)

Glutathionylation Mediates Angiotensin II–Induced eNOS Uncoupling, Amplifying NADPH Oxidase‐Dependent Endothelial Dysfunction
por: Galougahi, Keyvan Karimi, et al.
Publicado: (2014)

Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction
por: Murdoch, Colin E., et al.
Publicado: (2011)

Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling
por: Mistry, Rajesh K., et al.
Publicado: (2016)

Endothelial NADPH oxidase 4 protects against angiotensin II‐induced cardiac fibrosis and inflammation
por: Wang, Minshu, et al.
Publicado: (2021)

Role of NADPH Oxidase 4 in Corneal Endothelial Cells Is Mediated by Endoplasmic Reticulum Stress and Autophagy
por: Ma, Dae Joong, et al.
Publicado: (2023)

Spironolactone Inhibits NADPH Oxidase-Induced Oxidative Stress and Enhances eNOS in Human Endothelial Cells
por: Taye, Ashraf, et al.
Publicado: (2011)

Erratum to: Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction
por: Murdoch, Colin E., et al.
Publicado: (2014)

NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
por: Langbein, Heike, et al.
Publicado: (2016)

Correlation between NADPH oxidase-mediated oxidative stress and dysfunction of endothelial progenitor cell in hyperlipidemic patients
por: Li, Ting-Bo, et al.
Publicado: (2018)

Norepinephrine Induces Lung Microvascular Endothelial Cell Death by NADPH Oxidase-Dependent Activation of Caspase-3
por: Chignalia, Andreia Z., et al.
Publicado: (2020)

A novel monoclonal antibody reveals the enrichment of NADPH oxidase 5 in human splenic endothelial cells
por: Szeles, Zsolt, et al.
Publicado: (2023)

Blockade of TGF-β 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats
por: Miguel-Carrasco, José Luis, et al.
Publicado: (2012)

NADPH Oxidase and Neurodegeneration
por: Hernandes, Marina S, et al.
Publicado: (2012)

Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling
por: Chan, Shih-Hung, et al.
Publicado: (2017)

C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells
por: Manea, Simona-Adriana, et al.
Publicado: (2014)

Endothelial NADPH oxidase 4 mediates vascular endothelial growth factor receptor 2–induced intravitreal neovascularization in a rat model of retinopathy of prematurity
por: Wang, Haibo, et al.
Publicado: (2014)

Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction
por: Sukumar, Piruthivi, et al.
Publicado: (2013)

Formyl Peptide Receptor 1 Modulates Endothelial Cell Functions by NADPH Oxidase-Dependent VEGFR2 Transactivation
por: Cattaneo, Fabio, et al.
Publicado: (2018)

The role of acrolein for E-cigarette vapour condensate mediated activation of NADPH oxidase in cultured endothelial cells and macrophages
por: Kuntic, Ivana, et al.
Publicado: (2023)

NADPH Oxidases and Their Role in Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

NADPH Oxidases in Pain Processing
por: Kallenborn-Gerhardt, Wiebke, et al.
Publicado: (2022)

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
por: Othman, Amira, et al.
Publicado: (2013)

The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner
por: Tarafdar, Anuradha, et al.
Publicado: (2022)

Intermittent High Glucose Implements Stress-Induced Senescence in Human Vascular Endothelial Cells: Role of Superoxide Production by NADPH Oxidase
por: Maeda, Morihiko, et al.
Publicado: (2015)

Pulmonary Arterial Hypertension and Endothelial Dysfunction Is Linked to NADPH Oxidase-Derived Superoxide Formation in Venous Thrombosis and Pulmonary Embolism in Mice
por: Brandt, Moritz, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kcitrsf7llofp19ujdapp022rg