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KRAS and BRAF mutations in Iranian colorectal cancer patients: A systematic review and meta-analysis

BACKGROUND: Mutations in the EGFR signaling pathway play an important role in the development of colorectal cancer (CRC). Mutations in these genes, like KRAS and BRAF, affect the treatment strategies and associated with poor prognosis and relative resistance to anti-EGFR therapies. Our aim was to co...

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Detalles Bibliográficos
Autores principales: Yari, Abolfazl, Afzali, Asiyeh, Aalipour, Mostafa, Nakheai, Mehran, Zahedi, Mohammad Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911761/
https://www.ncbi.nlm.nih.gov/pubmed/33680376
http://dx.doi.org/10.22088/cjim.11.4.355