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Potential Dual Role of West Nile Virus NS2B in Orchestrating NS3 Enzymatic Activity in Viral Replication

West Nile virus (WNV) nonstructural protein 3 (NS3) harbors the viral triphosphatase and helicase for viral RNA synthesis and, together with NS2B, constitutes the protease responsible for polyprotein processing. NS3 is a soluble protein, but it is localized to specialized compartments at the rough e...

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Detalles Bibliográficos
Autores principales: Tseng, Alanna C., Nerurkar, Vivek R., Neupane, Kabi R., Kae, Helmut, Kaufusi, Pakieli H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911885/
https://www.ncbi.nlm.nih.gov/pubmed/33572517
http://dx.doi.org/10.3390/v13020216