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Nuclear Import of Adeno-Associated Viruses Imaged by High-Speed Single-Molecule Microscopy

Understanding the detailed nuclear import kinetics of adeno-associated virus (AAV) through the nuclear pore complex (NPC) is essential for the application of AAV capsids as a nuclear delivery instrument as well as a target for drug development. However, a comprehensive understanding of AAV transport...

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Detalles Bibliográficos
Autores principales: Junod, Samuel L., Saredy, Jason, Yang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911914/
https://www.ncbi.nlm.nih.gov/pubmed/33499411
http://dx.doi.org/10.3390/v13020167