TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish

The “distal axonopathy” hypothesis in amyotrophic lateral sclerosis (ALS) proposes that pathological changes occur at the neuromuscular junction (NMJ) early in the disease. While acetylcholinesterase (AChE) plays an important role in the functionality of the NMJ, its potential role in ALS remains un...

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Detalles Bibliográficos
Autores principales: Campanari, Maria-Letizia, Marian, Anca, Ciura, Sorana, Kabashi, Edor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911940/
https://www.ncbi.nlm.nih.gov/pubmed/33499374
http://dx.doi.org/10.3390/cells10020221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911940/
https://www.ncbi.nlm.nih.gov/pubmed/33499374
http://dx.doi.org/10.3390/cells10020221

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