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Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease

Identifying disease-modifying therapies for neurological diseases remains one of the greatest gaps in modern medicine. Herein, we present the rationale for intranasal (IN) delivery of deferoxamine (DFO), a high-affinity iron chelator, as a treatment for neurodegenerative and neurovascular disease wi...

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Detalles Bibliográficos
Autores principales: Kosyakovsky, Jacob, Fine, Jared M., Frey, William H., Hanson, Leah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911954/
https://www.ncbi.nlm.nih.gov/pubmed/33513737
http://dx.doi.org/10.3390/ph14020095