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Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias

Hereditary Spastic Paraplegias (HSPs) are a genetically diverse group of inherited neurological diseases with over 80 associated gene loci. Over the last decade, research into mechanisms underlying HSPs has led to an emerging interest in lysosome dysfunction. In this review, we highlight the differe...

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Detalles Bibliográficos
Autores principales: Edmison, Daisy, Wang, Luyu, Gowrishankar, Swetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911997/
https://www.ncbi.nlm.nih.gov/pubmed/33498913
http://dx.doi.org/10.3390/brainsci11020152