The α6 GABA(A) Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome

Tourette syndrome (TS) is a disabling neurodevelopmental disorder characterized by multiple, recurrent tics. The pharmacological treatment of TS is currently based on dopaminergic antagonists; however, these drugs are associated with extrapyramidal symptoms and other serious adverse events. Recent e...

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Detalles Bibliográficos
Autores principales: Cadeddu, Roberto, Knutson, Daniel E., Mosher, Laura J., Loizou, Stefanos, Odeh, Karen, Fisher, Janet L., Cook, James M., Bortolato, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912006/
https://www.ncbi.nlm.nih.gov/pubmed/33525455
http://dx.doi.org/10.3390/biom11020175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912006/
https://www.ncbi.nlm.nih.gov/pubmed/33525455
http://dx.doi.org/10.3390/biom11020175

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