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The α6 GABA(A) Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome
Tourette syndrome (TS) is a disabling neurodevelopmental disorder characterized by multiple, recurrent tics. The pharmacological treatment of TS is currently based on dopaminergic antagonists; however, these drugs are associated with extrapyramidal symptoms and other serious adverse events. Recent e...
Autores principales: | Cadeddu, Roberto, Knutson, Daniel E., Mosher, Laura J., Loizou, Stefanos, Odeh, Karen, Fisher, Janet L., Cook, James M., Bortolato, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912006/ https://www.ncbi.nlm.nih.gov/pubmed/33525455 http://dx.doi.org/10.3390/biom11020175 |
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