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How Does the Addition of Kollidon(®)VA64 Inhibit the Recrystallization and Improve Ezetimibe Dissolution from Amorphous Solid Dispersions?

Amorphization serves as a strategy for the improvement of poor dissolution characteristics of many drug compounds. However, in many formulations the content of polymeric stabilizer is high, which is undesirable from the perspective of future applications. Thus, studying the composition-dependent sta...

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Detalles Bibliográficos
Autores principales: Szafraniec-Szczęsny, Joanna, Antosik-Rogóż, Agata, Kurek, Mateusz, Gawlak, Karolina, Górska, Anna, Peralta, Sebastian, Knapik-Kowalczuk, Justyna, Kramarczyk, Daniel, Paluch, Marian, Jachowicz, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912050/
https://www.ncbi.nlm.nih.gov/pubmed/33498609
http://dx.doi.org/10.3390/pharmaceutics13020147