Nitroreductase Activites in Giardia lamblia: ORF 17150 Encodes a Quinone Reductase with Nitroreductase Activity

The intestinal diplomonadid Giardia lamblia is a causative agent of persistent diarrhea. Current treatments are based on nitro drugs, especially metronidazole. Nitro compounds are activated by reduction, yielding toxic intermediates. The enzymatic systems responsible for this activation are not comp...

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Detalles Bibliográficos
Autores principales: Müller, Joachim, Heller, Manfred, Uldry, Anne-Christine, Braga, Sophie, Müller, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912051/
https://www.ncbi.nlm.nih.gov/pubmed/33513906
http://dx.doi.org/10.3390/pathogens10020129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912051/
https://www.ncbi.nlm.nih.gov/pubmed/33513906
http://dx.doi.org/10.3390/pathogens10020129

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