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The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning

Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left–right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent PITX2 and, separately, the Forkhead transcription factor FOXC1 in...

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Detalles Bibliográficos
Autores principales: Chrystal, Paul W., French, Curtis R., Jean, Francesca, Havrylov, Serhiy, van Baarle, Suey, Peturson, Ann-Marie, Xu, Pengfei, Crump, J. Gage, Pilgrim, David B., Lehmann, Ordan J., Waskiewicz, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912076/
https://www.ncbi.nlm.nih.gov/pubmed/33530637
http://dx.doi.org/10.3390/genes12020170