Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition

Fluoxetine is still one of the most widely used antidepressants in the world. The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions. In a multidrug regimen, preemptive mitigation of drug–drug interactions requir...

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Detalles Bibliográficos
Autores principales: Deodhar, Malavika, Rihani, Sweilem B. Al, Darakjian, Lucy, Turgeon, Jacques, Michaud, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912198/
https://www.ncbi.nlm.nih.gov/pubmed/33498694
http://dx.doi.org/10.3390/pharmaceutics13020148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912198/
https://www.ncbi.nlm.nih.gov/pubmed/33498694
http://dx.doi.org/10.3390/pharmaceutics13020148

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