Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation

Defective interfering particles (DIPs) are naturally occurring products during virus replication in infected cells. DIPs contain defective viral genomes (DVGs) and interfere with replication and propagation of their corresponding standard viral genomes by competing for viral and cellular resources,...

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Detalles Bibliográficos
Autores principales: Johnson, Dylan M., Cubitt, Beatrice, Pfeffer, Tia L., de la Torre, Juan Carlos, Lukashevich, Igor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912207/
https://www.ncbi.nlm.nih.gov/pubmed/33573250
http://dx.doi.org/10.3390/v13020214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912207/
https://www.ncbi.nlm.nih.gov/pubmed/33573250
http://dx.doi.org/10.3390/v13020214

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