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Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation
Defective interfering particles (DIPs) are naturally occurring products during virus replication in infected cells. DIPs contain defective viral genomes (DVGs) and interfere with replication and propagation of their corresponding standard viral genomes by competing for viral and cellular resources,...
Autores principales: | Johnson, Dylan M., Cubitt, Beatrice, Pfeffer, Tia L., de la Torre, Juan Carlos, Lukashevich, Igor S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912207/ https://www.ncbi.nlm.nih.gov/pubmed/33573250 http://dx.doi.org/10.3390/v13020214 |
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