Prevention of Autoimmune Diabetes in NOD Mice by Dimethyl Fumarate

Oxidative stress plays critical roles in the pathogenesis of diabetes. This study tested the hypothesis that by protecting β-cells against oxidative stress and inflammation, an Nrf2 activator, dimethyl fumarate (DMF), may prevent or delay the onset of type 1 diabetes in non-obese diabetic (NOD) mice...

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Detalles Bibliográficos
Autores principales: Li, Shiri, Vaziri, Nosratola D., Swentek, Lourdes, Takasu, Chie, Vo, Kelly, Stamos, Michael J., Ricordi, Camillo, Ichii, Hirohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912218/
https://www.ncbi.nlm.nih.gov/pubmed/33572792
http://dx.doi.org/10.3390/antiox10020193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912218/
https://www.ncbi.nlm.nih.gov/pubmed/33572792
http://dx.doi.org/10.3390/antiox10020193

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