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Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus

Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels they are attractive drug leads in neuropharmacology. Recently, cone snails were found to have the capability to rapi...

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Detalles Bibliográficos
Autores principales: Armstrong, David A., Jin, Ai-Hua, Braga Emidio, Nayara, Lewis, Richard J., Alewood, Paul F., Rosengren, K. Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912261/
https://www.ncbi.nlm.nih.gov/pubmed/33530397
http://dx.doi.org/10.3390/md19020060