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Study the Antifungal and Ocular Permeation of Ketoconazole from Ophthalmic Formulations Containing Trans-Ethosomes Nanoparticles

Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is characterized by its poor aqueous solubility and high molecular weight, which might hamper its corneal permeation. The aim was to develop an ophthalmic formulation loaded with optimized trans-ethosomal vesicles to enhance...

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Detalles Bibliográficos
Autores principales: Ahmed, Tarek A., Alzahrani, Maram M., Sirwi, Alaa, Alhakamy, Nabil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912274/
https://www.ncbi.nlm.nih.gov/pubmed/33498849
http://dx.doi.org/10.3390/pharmaceutics13020151