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The Role of H3K4 Trimethylation in CpG Islands Hypermethylation in Cancer
CpG methylation in transposons, exons, introns and intergenic regions is important for long-term silencing, silencing of parasitic sequences and alternative promoters, regulating imprinted gene expression and determining X chromosome inactivation. Promoter CpG islands, although rich in CpG dinucleot...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912453/ https://www.ncbi.nlm.nih.gov/pubmed/33499170 http://dx.doi.org/10.3390/biom11020143 |