Heat Shock Protein Inhibitor 17-Allyamino-17-Demethoxygeldanamycin, a Potent Inductor of Apoptosis in Human Glioma Tumor Cell Lines, Is a Weak Substrate for ABCB1 and ABCG2 Transporters

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and has a poor prognosis. Complex genetic alterations and the protective effect of the blood–brain barrier (BBB) have so far hampered effective treatment. Here, we investigated the cytotoxic effects of heat shock protein...

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Detalles Bibliográficos
Autores principales: Pastvova, Nikola, Dolezel, Petr, Mlejnek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912456/
https://www.ncbi.nlm.nih.gov/pubmed/33573093
http://dx.doi.org/10.3390/ph14020107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912456/
https://www.ncbi.nlm.nih.gov/pubmed/33573093
http://dx.doi.org/10.3390/ph14020107

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