Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life. Their toxic effects result from irreversible blockade of the enzymes acetylcholinesterase and butyrylcholinesterase, which causes overstimulation of the chol...

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Detalles Bibliográficos
Autores principales: Jończyk, Jakub, Kukułowicz, Jędrzej, Łątka, Kamil, Malawska, Barbara, Jung, Young-Sik, Musilek, Kamil, Bajda, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912477/
https://www.ncbi.nlm.nih.gov/pubmed/33513955
http://dx.doi.org/10.3390/biom11020169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912477/
https://www.ncbi.nlm.nih.gov/pubmed/33513955
http://dx.doi.org/10.3390/biom11020169

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