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Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
Poisoning with organophosphorus compounds used as pesticides or misused as chemical weapons remains a serious threat to human health and life. Their toxic effects result from irreversible blockade of the enzymes acetylcholinesterase and butyrylcholinesterase, which causes overstimulation of the chol...
Autores principales: | Jończyk, Jakub, Kukułowicz, Jędrzej, Łątka, Kamil, Malawska, Barbara, Jung, Young-Sik, Musilek, Kamil, Bajda, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912477/ https://www.ncbi.nlm.nih.gov/pubmed/33513955 http://dx.doi.org/10.3390/biom11020169 |
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