Acquired radioresistance in cancer associated fibroblasts is concomitant with enhanced antioxidant potential and DNA repair capacity

BACKGROUND: Cancer-associated fibroblasts (CAFs) are a major component of the cancer stroma, and their response to therapeutic treatments likely impacts the outcome. We tested the hypothesis that CAFs develop unique characteristics that enhance their resistance to ionizing radiation. METHODS: CAFs w...

Descripción completa

Detalles Bibliográficos
Autores principales: Domogauer, Jason D., de Toledo, Sonia M., Howell, Roger W., Azzam, Edouard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912493/
https://www.ncbi.nlm.nih.gov/pubmed/33637118
http://dx.doi.org/10.1186/s12964-021-00711-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912493/
https://www.ncbi.nlm.nih.gov/pubmed/33637118
http://dx.doi.org/10.1186/s12964-021-00711-4

Ejemplares similares