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Ginsenoside Rg3 inhibits pulmonary fibrosis by preventing HIF-1α nuclear localisation
BACKGROUND: Excessive fibroblast proliferation during pulmonary fibrosis leads to structural abnormalities in lung tissue and causes hypoxia and cell injury. However, the mechanisms and effective treatment are still limited. METHODS: In vivo, we used bleomycin to induce pulmonary fibrosis in mice. I...
Autores principales: | Fu, Zhuo, Xu, Yong-sheng, Cai, Chun-quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912494/ https://www.ncbi.nlm.nih.gov/pubmed/33639908 http://dx.doi.org/10.1186/s12890-021-01426-5 |
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