Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

Cancer cells produce high levels of mitochondria-associated reactive oxygen species (ROS) that can damage macromolecules, but also promote cell signaling and proliferation. Therefore, mitochondria-targeted antioxidants have been suggested to be useful in anti-cancer therapy, but no studies have conv...

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Detalles Bibliográficos
Autores principales: Le Gal, Kristell, Wiel, Clotilde, Ibrahim, Mohamed X., Henricsson, Marcus, Sayin, Volkan I., Bergo, Martin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912553/
https://www.ncbi.nlm.nih.gov/pubmed/33499262
http://dx.doi.org/10.3390/antiox10020163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912553/
https://www.ncbi.nlm.nih.gov/pubmed/33499262
http://dx.doi.org/10.3390/antiox10020163

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