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Mesoporous Polydopamine Nanoparticles Attenuate Morphine Tolerance in Neuropathic Pain Rats by Inhibition of Oxidative Stress and Restoration of the Endogenous Antioxidant System

Oxidative stress resulting from reactive oxygen species (ROS) is known to play a key role in numerous neurological disorders, including neuropathic pain. Morphine is one of the commonly used opioids for pain management. However, long-term administration of morphine results in morphine antinociceptiv...

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Detalles Bibliográficos
Autores principales: Kuthati, Yaswanth, Busa, Prabhakar, Tummala, Srikrishna, Rao, Vaikar Navakanth, Davuluri, Venkata Naga Goutham, Ho, Yen-Peng, Wong, Chih-Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912557/
https://www.ncbi.nlm.nih.gov/pubmed/33572871
http://dx.doi.org/10.3390/antiox10020195