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The Pancreatic β-Cell: The Perfect Redox System

Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H(2)O(2) production for glucose-stimulated insulin secretion (GSIS). There is a logical summation...

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Detalles Bibliográficos
Autores principales: Ježek, Petr, Holendová, Blanka, Jabůrek, Martin, Tauber, Jan, Dlasková, Andrea, Plecitá-Hlavatá, Lydie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912581/
https://www.ncbi.nlm.nih.gov/pubmed/33572903
http://dx.doi.org/10.3390/antiox10020197