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The Pancreatic β-Cell: The Perfect Redox System
Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H(2)O(2) production for glucose-stimulated insulin secretion (GSIS). There is a logical summation...
Autores principales: | Ježek, Petr, Holendová, Blanka, Jabůrek, Martin, Tauber, Jan, Dlasková, Andrea, Plecitá-Hlavatá, Lydie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912581/ https://www.ncbi.nlm.nih.gov/pubmed/33572903 http://dx.doi.org/10.3390/antiox10020197 |
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