Betulinic Acid Alleviates Spleen Oxidative Damage Induced by Acute Intraperitoneal Exposure to T-2 Toxin by Activating Nrf2 and Inhibiting MAPK Signaling Pathways

T-2 toxin, which is mainly produced by specific strains of Fusarium in nature, can induce immunotoxicity and oxidative stress, resulting in immune organ dysfunction and apoptosis. Betulinic acid (BA), a pentacyclic triterpenoids from nature plants, has been demonstrated to possess immunomodulating a...

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Detalles Bibliográficos
Autores principales: Kong, Li, Zhu, Lijuan, Yi, Xianglian, Huang, You, Zhao, Haoqiang, Chen, Yazhi, Yuan, Zhihang, Wen, Lixin, Wu, Jing, Yi, Jine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912660/
https://www.ncbi.nlm.nih.gov/pubmed/33499152
http://dx.doi.org/10.3390/antiox10020158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912660/
https://www.ncbi.nlm.nih.gov/pubmed/33499152
http://dx.doi.org/10.3390/antiox10020158

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