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Liposomal Bupivacaine (Bupigel) Demonstrates Minimal Local Nerve Toxicity in a Rabbit Functional Model

We previously reported the development of a novel formulation of an ultra-long-acting local anesthetic based on bupivacaine encapsulated in large multivesicular liposomes (Bupisomes) embedded in hydrogel. This formulation (Bupigel) prolonged bupivacaine release from the formulation in dissolution-li...

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Detalles Bibliográficos
Autores principales: Bavli, Yaelle, Rabie, Malcolm, Fellig, Yakov, Nevo, Yoram, Barenholz, Yechezkel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912710/
https://www.ncbi.nlm.nih.gov/pubmed/33535418
http://dx.doi.org/10.3390/pharmaceutics13020185