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Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model

Immune checkpoint inhibitors have great potential for the treatment of gliomas; however, their therapeutic efficacy has been partially limited by their inability to efficiently cross the blood–brain barrier (BBB). The objective of this study was to evaluate the capability of focused-ultrasound-media...

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Detalles Bibliográficos
Autores principales: Ye, Dezhuang, Yuan, Jinyun, Yue, Yimei, Rubin, Joshua B., Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912734/
https://www.ncbi.nlm.nih.gov/pubmed/33535531
http://dx.doi.org/10.3390/pharmaceutics13020190