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Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model
Immune checkpoint inhibitors have great potential for the treatment of gliomas; however, their therapeutic efficacy has been partially limited by their inability to efficiently cross the blood–brain barrier (BBB). The objective of this study was to evaluate the capability of focused-ultrasound-media...
Autores principales: | Ye, Dezhuang, Yuan, Jinyun, Yue, Yimei, Rubin, Joshua B., Chen, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912734/ https://www.ncbi.nlm.nih.gov/pubmed/33535531 http://dx.doi.org/10.3390/pharmaceutics13020190 |
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