Mycobacterium tuberculosis Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling

The Mycobacterium tuberculosis (M. tb) genome encodes a large number of hypothetical proteins, which need to investigate their role in physiology, virulence, pathogenesis, and host interaction. To explore the role of hypothetical protein Rv0580c, we constructed the recombinant Mycobacterium smegmati...

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Detalles Bibliográficos
Autores principales: Ali, Md Kaisar, Nzungize, Lambert, Abbas, Khushnood, Eckzechel, Nzaou Stech Anomene, Abo-kadoum, M. A., Moure, Ulrich Aymard Ekomi, Asaad, Mohammed, Alam, Aftab, Xu, Junqi, Xie, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912736/
https://www.ncbi.nlm.nih.gov/pubmed/33535567
http://dx.doi.org/10.3390/pathogens10020143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912736/
https://www.ncbi.nlm.nih.gov/pubmed/33535567
http://dx.doi.org/10.3390/pathogens10020143

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