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Mycobacterium tuberculosis Rv0580c Impedes the Intracellular Survival of Recombinant Mycobacteria, Manipulates the Cytokines, and Induces ER Stress and Apoptosis in Host Macrophages via NF-κB and p38/JNK Signaling
The Mycobacterium tuberculosis (M. tb) genome encodes a large number of hypothetical proteins, which need to investigate their role in physiology, virulence, pathogenesis, and host interaction. To explore the role of hypothetical protein Rv0580c, we constructed the recombinant Mycobacterium smegmati...
Autores principales: | Ali, Md Kaisar, Nzungize, Lambert, Abbas, Khushnood, Eckzechel, Nzaou Stech Anomene, Abo-kadoum, M. A., Moure, Ulrich Aymard Ekomi, Asaad, Mohammed, Alam, Aftab, Xu, Junqi, Xie, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912736/ https://www.ncbi.nlm.nih.gov/pubmed/33535567 http://dx.doi.org/10.3390/pathogens10020143 |
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