Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole- and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein

Cancer is a multifactorial disease necessitating identification of novel targets for its treatment. Inhibition of Bcl-2 for triggered pro-apoptotic signaling is considered a promising strategy for cancer treatment. Within the current work, we aimed to design and synthesize a new series of benzimidaz...

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Detalles Bibliográficos
Autores principales: Nagy, Manar I., Darwish, Khaled M., Kishk, Safaa M., Tantawy, Mohamed A., Nasr, Ali M., Qushawy, Mona, Swidan, Shady A., Mostafa, Samia M., Salama, Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912796/
https://www.ncbi.nlm.nih.gov/pubmed/33535550
http://dx.doi.org/10.3390/ph14020113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912796/
https://www.ncbi.nlm.nih.gov/pubmed/33535550
http://dx.doi.org/10.3390/ph14020113

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