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Val16A SOD2 Polymorphism Promotes Epithelial–Mesenchymal Transition Antagonized by Muscadine Grape Skin Extract in Prostate Cancer Cells

Epithelial–mesenchymal transition (EMT), a key event in cancer metastasis, allows polarized epithelial cells to assume mesenchymal morphologies, enhancing invasiveness and migration, and can be induced by reactive oxygen species (ROS). Val16A (Ala) SOD2 polymorphism has been associated with increase...

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Detalles Bibliográficos
Autores principales: Sweeney, Janae D., Debeljak, Marija, Riel, Stacy, Millena, Ana Cecilia, Eshleman, James R., Paller, Channing J., Odero-Marah, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912849/
https://www.ncbi.nlm.nih.gov/pubmed/33535682
http://dx.doi.org/10.3390/antiox10020213