Cargando…

Val16A SOD2 Polymorphism Promotes Epithelial–Mesenchymal Transition Antagonized by Muscadine Grape Skin Extract in Prostate Cancer Cells

Epithelial–mesenchymal transition (EMT), a key event in cancer metastasis, allows polarized epithelial cells to assume mesenchymal morphologies, enhancing invasiveness and migration, and can be induced by reactive oxygen species (ROS). Val16A (Ala) SOD2 polymorphism has been associated with increase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sweeney, Janae D., Debeljak, Marija, Riel, Stacy, Millena, Ana Cecilia, Eshleman, James R., Paller, Channing J., Odero-Marah, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912849/ https://www.ncbi.nlm.nih.gov/pubmed/33535682 http://dx.doi.org/10.3390/antiox10020213

Ejemplares similares

Analytical Validation of SOD2 Genotyping
por: Debeljak, Marija, et al.
Publicado: (2022)

CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE)
por: Burton, Liza J., et al.
Publicado: (2019)

Muscadine grape skin extract reverts snail-mediated epithelial mesenchymal transition via superoxide species in human prostate cancer cells
por: Burton, Liza J, et al.
Publicado: (2014)

Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis
por: Burton, Liza J., et al.
Publicado: (2016)

Determination of Fertility-Related Traits in Muscadine Grape Population
por: Campbell, Jiovan, et al.
Publicado: (2021)

Genetic Diversity of Wild and Cultivated Muscadine Grapes (Vitis rotundifolia Michx.)
por: Buck, Kenneth, et al.
Publicado: (2022)

Biometrics Assessment of Cluster- and Berry-Related Traits of Muscadine Grape Population
por: Campbell, Jiovan, et al.
Publicado: (2021)

Investigation of Antioxidant and Cytotoxicity Activities of Chocolate Fortified with Muscadine Grape Pomace
por: Darwish, Ahmed G., et al.
Publicado: (2023)

Evaluation of Biochemical Juice Attributes and Color-Related Traits in Muscadine Grape Population
por: Campbell, Jiovan, et al.
Publicado: (2021)

Untargeted Metabolomics and Antioxidant Capacities of Muscadine Grape Genotypes during Berry Development
por: Darwish, Ahmed G., et al.
Publicado: (2021)

Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40
por: Ignacio, Diane N., et al.
Publicado: (2019)

Multi-year Quantitative Evaluation of Stilbenoids Levels Among Selected Muscadine Grape Cultivars
por: Kambiranda, Devaiah M., et al.
Publicado: (2019)

Glutathione S-transferase: a candidate gene for berry color in muscadine grapes (Vitis rotundifolia)
por: Varanasi, Aruna, et al.
Publicado: (2022)

Profile of Polyphenol Compounds of Five Muscadine Grapes Cultivated in the United States and in Newly Adapted Locations in China
por: Wei, Zheng, et al.
Publicado: (2017)

A Polyphenol-Rich Extract From Muscadine Grapes Inhibits Triple-Negative Breast Tumor Growth
por: Collard, Marianne, et al.
Publicado: (2020)

A recessive mutation in muscadine grapes causes berry color-loss without influencing anthocyanin pathway
por: Ismail, Ahmed, et al.
Publicado: (2022)

A Polyphenol-Rich Extract from Muscadine Grapes Prevents Hypertension-Induced Diastolic Dysfunction and Oxidative Stress
por: Patil, Pooja D., et al.
Publicado: (2022)

Transcriptional profiling of two muscadine grape cultivars “Carlos” and “Noble” to reveal new genes, gene regulatory networks, and pathways that involved in grape berry ripening
por: Chang, Yuru, et al.
Publicado: (2022)

Chemical Composition, In Vitro Antioxidant Potential, and Antimicrobial Activities of Essential Oils and Hydrosols from Native American Muscadine Grapes
por: Georgiev, Vasil, et al.
Publicado: (2019)

Molecular Characterization and Phylogenetic Analysis of MADS-Box Gene VroAGL11 Associated with Stenospermocarpic Seedlessness in Muscadine Grapes
por: Rahman, M Atikur, et al.
Publicado: (2021)

Targeted UHPLC-MS Analysis Reveals Disparate Polyphenol Composition and Concentration in Muscadine Grape Supplements with Proportional Antioxidant Activity
por: Chappell, Mark C., et al.
Publicado: (2022)

Larrea tridentata Extract Mitigates Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
por: Morán-Santibañez, Karla, et al.
Publicado: (2019)

Association of the SOD2 Polymorphism (Val16Ala) and SOD Activity with Vaso-occlusive Crisis and Acute Splenic Sequestration in Children with Sickle Cell Anemia
por: Farias, Isabela Cristina Cordeiro, et al.
Publicado: (2018)

Polymorphism of MnSOD (Val16Ala) gene in pregnancies with blighted ovum: A case-control study
por: Moshtaghi, Asiyeh, et al.
Publicado: (2017)

Synergistic Action of Stilbenes in Muscadine Grape Berry Extract Shows Better Cytotoxic Potential Against Cancer Cells Than Resveratrol Alone
por: Balasubramani, Subramani Paranthaman, et al.
Publicado: (2019)

Silicon Alleviate Hypoxia Stress by Improving Enzymatic and Non-enzymatic Antioxidants and Regulating Nutrient Uptake in Muscadine Grape (Muscadinia rotundifolia Michx.)
por: Iqbal, Zafar, et al.
Publicado: (2021)

Probiotic and Muscadine Grape Extract Interventions Shift the Gut Microbiome and Improve Metabolic Parameters in Female C57BL/6 Mice
por: Newman, Tiffany M., et al.
Publicado: (2023)

Development of a High-Density Genetic Map for Muscadine Grape Using a Mapping Population from Selfing of the Perfect-Flowered Vine ‘Dixie’
por: Lytkin, Kirill, et al.
Publicado: (2022)

Methotrexate-Related Response on Human Peripheral Blood Mononuclear Cells May Be Modulated by the Ala16Val-SOD2 Gene Polymorphism
por: Barbisan, Fernanda, et al.
Publicado: (2014)

Link between MnSOD Ala16Val (rs4880) polymorphism and asthma risk is insignificant from sequential meta-analysis
por: Alhobeira, Hazza A, et al.
Publicado: (2020)

The comparative study among different fractions of muscadine grape ‘Noble’ pomace extracts regarding anti-oxidative activities, cell cycle arrest and apoptosis in breast cancer
por: Luo, Jianming, et al.
Publicado: (2017)

Comparison of the Fruit Volatile Profiles of Five Muscadine Grape Cultivars (Vitis rotundifolia Michx.) Using HS-SPME-GC/MS Combined With Multivariate Statistical Analysis
por: Deng, Honghong, et al.
Publicado: (2021)

Association between MnSOD Val16Ala Polymorphism and Cancer Risk: Evidence from 33,098 Cases and 37,831 Controls
por: Wang, Ping, et al.
Publicado: (2018)

SOD2 gene Val16Ala polymorphism is associated with macroalbuminuria in Mexican Type 2 Diabetes patients: a comparative study and meta-analysis
por: Ascencio-Montiel, Iván de Jesús, et al.
Publicado: (2013)

Oligogenic basis of sporadic ALS: The example of SOD1 p.Ala90Val mutation
por: Kuuluvainen, Liina, et al.
Publicado: (2019)

Transcriptome Profiling During Muscadine Berry Development Reveals the Dynamic of Polyphenols Metabolism
por: Ismail, Ahmed, et al.
Publicado: (2022)

Metabolomics Integrated with HPLC–MS Reveals the Crucial Antioxidant Compounds of Muscadine Wine
por: Xue, Fei, et al.
Publicado: (2022)

Draft Genome Sequences of Xylella fastidiosa subsp. fastidiosa Strains OK3, VB11, and NOB1, Isolated from Bunch and Muscadine Grapes Grown in Southern Mississippi
por: Mavrodi, Olga V., et al.
Publicado: (2020)

Association between MnSOD Activity and Cognitive Impairment in Unmedicated First-Episode Schizophrenia: Regulated by MnSOD Ala-9Val Gene Polymorphism
por: Wang, Dong Mei, et al.
Publicado: (2022)

Superoxide imbalance triggered by Val16Ala‐SOD2 polymorphism increases the risk of depression and self‐reported psychological stress in free‐living elderly people
por: da Cruz Jung, Ivo Emilio, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_edoe87t3s5olaklmj2i4n0esot