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Deoxycholic Acid Upregulates Serum Golgi Protein 73 through Activating NF-κB Pathway and Destroying Golgi Structure in Liver Disease

Golgi protein 73 (GP73) is upregulated in a variety of liver diseases, yet the detailed mechanism is poorly characterized. We analyzed GP73 in a retrospective cohort including 4211 patients with chronic liver disease (CLD) or hepatocellular carcinoma (HCC). The effect of deoxycholic acid (DCA) and n...

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Detalles Bibliográficos
Autores principales: Yang, Danli, Yao, Mingjie, Yan, Ying, Liu, Yanna, Wen, Xiajie, Chen, Xiangmei, Lu, Fengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913056/
https://www.ncbi.nlm.nih.gov/pubmed/33540642
http://dx.doi.org/10.3390/biom11020205