Cargando…

Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study

Glyoxalase 1 (Glo1) is the rate-limiting enzyme in the detoxification of methylglyoxal (MGO) into D-lactate. MGO is a major precursor of advanced glycation endproducts (AGEs), and both are associated with development of age-related diseases. Since genetic variation in GLO1 may alter the expression a...

Descripción completa

Detalles Bibliográficos
Autores principales: Maasen, Kim, Hanssen, Nordin M. J., van der Kallen, Carla J. H., Stehouwer, Coen D. A., van Greevenbroek, Marleen M. J., Schalkwijk, Casper G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913097/
https://www.ncbi.nlm.nih.gov/pubmed/33540757
http://dx.doi.org/10.3390/antiox10020219