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Preservation of Organ Function in Locally Advanced Non-Metastatic Gastrointestinal Stromal Tumors (GIST) of the Stomach by Neoadjuvant Imatinib Therapy

SIMPLE SUMMARY: This study reports a single-center analysis of 55 patients with primary, locally advanced gastric GIST treated with imatinib mesylate (IM) preoperatively for a median of 10 months. The therapy yielded shrinkage of median tumor size from 113 mm to 62 mm. This facilitated 50 patients t...

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Detalles Bibliográficos
Autores principales: Vassos, Nikolaos, Jakob, Jens, Kähler, Georg, Reichardt, Peter, Marx, Alexander, Dimitrakopoulou-Strauss, Antonia, Rathmann, Nils, Wardelmann, Eva, Hohenberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913129/
https://www.ncbi.nlm.nih.gov/pubmed/33546113
http://dx.doi.org/10.3390/cancers13040586