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Regulation, Activation and Function of Caspase-11 during Health and Disease

Caspase-11 is a pro-inflammatory enzyme that is stringently regulated during its expression and activation. As caspase-11 is not constitutively expressed in cells, it requires a priming step for its upregulation, which occurs following the stimulation of pathogen and cytokine receptors. Once express...

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Detalles Bibliográficos
Autores principales: Agnew, Aidan, Nulty, Ciara, Creagh, Emma M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913190/
https://www.ncbi.nlm.nih.gov/pubmed/33546173
http://dx.doi.org/10.3390/ijms22041506