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Invasive and Noninvasive Nonfunctioning Gonadotroph Pituitary Tumors Differ in DNA Methylation Level of LINE-1 Repetitive Elements

Purpose: Epigenetic dysregulation plays a role in pituitary tumor pathogenesis. Some differences in DNA methylation were observed between invasive and noninvasive nonfunctioning gonadotroph tumors. This study sought to determine the role of DNA methylation changes in repetitive LINE-1 elements in no...

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Detalles Bibliográficos
Autores principales: Rusetska, Natalia, Kober, Paulina, Król, Sylwia Katarzyna, Boresowicz, Joanna, Maksymowicz, Maria, Kunicki, Jacek, Bonicki, Wiesław, Bujko, Mateusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913198/
https://www.ncbi.nlm.nih.gov/pubmed/33546126
http://dx.doi.org/10.3390/jcm10040560