Synthesis and Anti-Hepatocarcinoma Effect of Amino Acid Derivatives of Pyxinol and Ocotillol

Aiming at seeking an effective anti-hepatocarcinoma drug with low toxicity, a total of 24 amino acid derivatives (20 new along with 4 known derivatives) of two active ocotillol-type sapogenins (pyxinol and ocotillol) were synthesized. Both in vitro and in vivo anti-hepatocarcinoma effects of derivat...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Yu, Hui, Fu, Shuzheng, Tan, Luying, Liu, Junli, Zhou, Baisong, Li, Le, Liu, Yunhe, Wang, Caixia, Li, Pingya, Liu, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913291/
https://www.ncbi.nlm.nih.gov/pubmed/33546225
http://dx.doi.org/10.3390/molecules26040780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913291/
https://www.ncbi.nlm.nih.gov/pubmed/33546225
http://dx.doi.org/10.3390/molecules26040780

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