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Exosomal miR-335 derived from mature dendritic cells enhanced mesenchymal stem cell-mediated bone regeneration of bone defects in athymic rats

BACKGROUND: Transplantation of bone marrow-derived mesenchymal stem cells (BM-MSCs) embedded in a bio-compatible matrix has been demonstrated as a promising strategy for the treatment of bone defects. This study was designed to explore the effect and mechanism of exosomes derived from mature dendrit...

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Detalles Bibliográficos
Autores principales: Cao, Zhongliu, Wu, Yanfeng, Yu, Lingling, Zou, Lingfeng, Yang, Liu, Lin, Sijian, Wang, Jue, Yuan, Zhen, Dai, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913386/
https://www.ncbi.nlm.nih.gov/pubmed/33637046
http://dx.doi.org/10.1186/s10020-021-00268-5