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Silencing of MEG3 attenuated the role of lipopolysaccharides by modulating the miR-93-5p/PTEN pathway in Leydig cells

BACKGROUND: Leydig cells reflect the activation of inflammation, decrease of androgen production, inhibition of cell growth and promotion of cell apoptosis under orchitis. Maternally expressed gene 3 (MEG3) exerts a crucial role in various human diseases, but under orchitis, the role and underlying...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, He, Jingliang, Chen, Jinbo, Cui, Yu, Ou, Zhenyu, Zu, Xiongbing, Liu, Nenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913434/
https://www.ncbi.nlm.nih.gov/pubmed/33639974
http://dx.doi.org/10.1186/s12958-021-00712-5