Promoter-proximal CTCF-binding promotes long-range-enhancer dependent gene activation

The CCCTC-binding factor (CTCF) works together with the cohesin complex to drives the formation of chromatin loops and topologically associating domains, but its role in gene regulation has not been fully defined. Here, we investigated the effects of acute CTCF loss on chromatin architecture and tra...

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Detalles Bibliográficos
Autores principales: Kubo, Naoki, Ishii, Haruhiko, Xiong, Xiong, Bianco, Simona, Meitinger, Franz, Hu, Rong, Hocker, James D., Conte, Mattia, Gorkin, David, Yu, Miao, Li, Bin, Dixon, Jesse R., Hu, Ming, Nicodemi, Mario, Zhao, Huimin, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913465/
https://www.ncbi.nlm.nih.gov/pubmed/33398174
http://dx.doi.org/10.1038/s41594-020-00539-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913465/
https://www.ncbi.nlm.nih.gov/pubmed/33398174
http://dx.doi.org/10.1038/s41594-020-00539-5

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