Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells

Herein, the activity of adamantanyl-tethered-biphenyl amines (ATBAs) as oestrogen receptor alpha (ERα) modulating ligands is reported. Using an ERα competitor assay it was demonstrated that ATBA compound 3-(adamantan-1-yl)-4-methoxy-N-(4-(trifluoromethyl) phenyl) aniline (AMTA) exhibited an inhibito...

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Detalles Bibliográficos
Autores principales: Basappa, Basappa, Chumadathil Pookunoth, Baburajeev, Shinduvalli Kempasiddegowda, Mamatha, Knchugarakoppal Subbegowda, Rangappa, Lobie, Peter E., Pandey, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913524/
https://www.ncbi.nlm.nih.gov/pubmed/33546391
http://dx.doi.org/10.3390/molecules26040783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913524/
https://www.ncbi.nlm.nih.gov/pubmed/33546391
http://dx.doi.org/10.3390/molecules26040783

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