NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na(+) solution with a moderate K(+) tolerance

Vast G-quadruplexes (GQs) are primarily folded by one, two, or four G-rich oligomers, rarely with an exception. Here, we present the first NMR solution structure of a trimolecular GQ (tri-GQ) that is solely assembled by the self-trimerization of d(GTTAGG), preferentially in Na(+) solution tolerant t...

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Detalles Bibliográficos
Autores principales: Jing, Haitao, Fu, Wenqiang, Hu, Wenxuan, Xu, Suping, Xu, Xiaojuan, He, Miao, Liu, Yangzhong, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913680/
https://www.ncbi.nlm.nih.gov/pubmed/33524157
http://dx.doi.org/10.1093/nar/gkab028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913680/
https://www.ncbi.nlm.nih.gov/pubmed/33524157
http://dx.doi.org/10.1093/nar/gkab028

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